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In addition, Ca<sup>2+<\/sup> channels and signaling pathways in macrophages contributing to cardiac remodeling through cardiocrine signaling will be identified.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>DZHK DZHK Targeting Ca2+-dependent arrhythmias and remodeling via inhibition of TRPC and endo-lysosomal channels We will develop therapeutic strategies to target TRPC, ORAI and endo-lysosomal channels with small molecules and by base and prime editing approaches. In addition, Ca2+ channels and signaling pathways in macrophages contributing to cardiac remodeling through cardiocrine signaling will be identified. &nbsp; &nbsp;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-pagefull.php","meta":{"footnotes":""},"class_list":["post-4228","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"DZHK DZHK Targeting Ca2+-dependent arrhythmias and remodeling via inhibition of TRPC and endo-lysosomal channels We will develop therapeutic strategies to target TRPC, ORAI and endo-lysosomal channels with small molecules and by base and prime editing approaches. 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